Topiramate


 * Topiramate**


 * Topiramate** (brand name **Topamax**) is an [|anticonvulsant] (antiepilepsy) drug. It was originally produced by [|Ortho-McNeil Neurologics] and Noramco, Inc., both divisions of the [|Johnson & Johnson] Corporation. This medication was discovered in 1979 by [|Bruce E. Maryanoff] and Joseph F. Gardocki during their research work at McNeil Pharmaceutical. [|[1]] [|[2]] [|[3]] Generic versions are available in Canada and these were approved by the [|Food and Drug Administration] (FDA) in September 2006. [|Mylan Pharmaceuticals] was recently granted final approval for generic topiramate 25, 100, and 200 mg tablets and sprinkle capsules by the FDA for sale in the [|United States] . 50 mg tablets were granted tentative approval. [|[4]] The last patent for topiramate in the U.S. was for pediatric use; this patent expired on February 28, 2009. [|[5]]

An anticonvulsant drug by Johnson & Johnson in 1979. Approved by the FDA the drug is used to treat epilepsy in kids and most recently migraines. Topiramate inhibits carbonic anhydrase. The drug has many side effects such as any other pharmaceutical drug; depression, agitation, fainting, etc.