Benzyl+Cyanide

Benzyl cyanide is produced by the reaction of benzyl chloride with sodium cyanide.
 * Benzyl cyanide ** (abbreviated ** BnCN ** ) is an organic compound with the chemical formula C6H5CH2CN. This colorless oily aromatic liquid is a precursor to several derivatives.

The compound's most important reactions involve the "active methylene group," which is readily functionalized following deprotonation.

BnCN it is an important intermediate for a variety of useful – and some dangerous - compounds. It is used in the production of phenobarbital, methylphenidate , and other amphetamines. For this reason it is on the U.S.'s DEA List I of chemicals. It is also used to make methadone and also pethidine and ketobemidone (if further substituted).

BnCN is the precursor to sibutramine and related compounds. For example, BnCN reacts with 1,3-dihalopropane in the presence of a strong base to form the cyclobutane precursor to SEP-225289. One route to prolintane involves Clemmensen reduction of the pyrovalerone compound. The Clemmensen reduction is avoided if the synthesis starts with alkylation of BnCN followed by hydrolysis and reductive amination.

[[image:Benzyl_Cyanide.jpg]]
Benzyl cyanide, like related benzyl derivatives, is an irritant to the skin and eyes. It is toxic and produces hydrogen cyanide when burned.


 * < CAS ||< 140-29-4 ||
 * < Molecular Formula ||< C8H7N ||
 * < Molecular Weight ||< 117.15 ||
 * < Appearance ||<  ||
 * < Melting point ||< -23.8ºC ||
 * < Boiling point ||< 233.5ºC ||
 * < Assay ||< ≥99.5% ||
 * < Water ||< ≤0.2% ||
 * < Use ||< Used to product medicine,pedtcide intermediates ,Can be used in the production of phenyl acetic acid ,phenyl amide ,diphenyl acetonitrile ,phoxim and so on ||
 * < Packing ||< 200kgplastic pail. ||