Metformin

An oral antidiabetic drug in the diguanide class It is the first-line drug of choice for the treatment of type 2 diabetes, in particular, in overweight and obese people and those with normal kidney function Its use in gestational diabetes has been limited b safety concerns It is also used in the treatment of polycystic ovary syndrome and has been investigated for other diseases where insulin resistance may be an important factor Metformin works by suppressing glucose production by the liver Metformine is the only antidiabetic drug that has been conclusively shown to prevent the cardiovasuclar complications of diaetes It helps reduce LDL cholestrol and triglyceride levels and is not associated with weight gain